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Friday, December 11, 2015

Drug- induced Lupus


CAUSATIVE DRUGS
 
Definite
Procainamide, hydralazine, minocycline, diltiazem, penicillamine, isoniazid (INH), quinidine, anti-tumor necrosis factor (TNF) alpha therapy (most commonly with infliximab and etanercept), interferon-alfa, methyldopa, chlorpromazine, and practolol

Probable 
Anticonvulsants (phenytoin, mephenytoin, trimethadione, ethosuximide, carbamazepine), antithyroid drugs, antimicrobial agents (sulfonamides, rifampin, nitrofurantoin), beta blockers, lithium, paraaminosalicylate, captopril, interferon gamma, hydrochlorothiazide, glyburide, sulfasalazine, terbinafine, amiodarone, ticlopidine, and docetaxel
 
Possible
Gold salts, penicillin, tetracycline, reserpine, valproate, statins (eg, lovastatin, simvastatin, and atorvastatin), griseofulvin, gemfibrozil, valproate, lamotrigine, ophthalmic timolol, and 5-aminosalicylate.

Reference:

  1. Up-To-Date

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