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Monday, November 7, 2016

Enteral Feeding: PPI and Ranitide



Cap Omeprazole 20mg
(gelatin capsule)
For swallowing difficulties:
  • Can open and contents swallowed or dispersed in slightly acidic fluid 
  • Exm: juice, sour milk, non-carbonated water

Extemporaneous Preparation:
  • 20 mg capsule contents can be dissolved in 10 mL of
  • 8.4% sodium bicarbonate to give a 2 mg_mL solution
  • stable for 14 days at RT and 45 days in
  • can be administered via nasogastric, duodenal or jejunal tube without risk of blockage or reduced efficacy.
Tab Pantoprazole 40mg
(enteric coated)
Not to be chewed or crushed
Tab Esomeprazole 20/40mg
(Gastro-resistant tablet)

The formulation is a film-coated tablet containing a compressed core of enteric coated microgranules.
  • Nexium is licensed for administration via a gastric tube.
Tab Ranitidine 150mg
Enteral Tube
  • No specific data on enteral tube administration are available for these formulations
Extemporaneous Preparation:
  • Can be prepared into a 15mg/ml syrup solution using distilled water and syrup BP
Reference
Handbook of Drug Administration via Enteral Feeding Tubes. British Pharmaceutical Nutrition Group

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