Benzodiazepine |
Onset of Action2
|
Peak Onset (hrs) |
Half-life parent (hrs) |
Half-life metabolite (hrs) |
Comparative Oral Dose |
Long Acting |
|||||
Diazepam1 (Valium®) |
Rapid (po, IV) |
1(po) |
20-50 |
3-100 |
5 mg |
Intermediate Acting |
|||||
Alprazolam1 (Xanax®) |
Int. |
0.7-1.6 |
6-20 |
- |
0.5mg |
Clonazepam1 (Rivotril®) |
Int. |
1-4 |
18-39 |
- |
0.25mg |
Lorazepam1 (Ativan®) |
Int. (po), Rapid (sl, IV) |
1-1.5 (po) |
10-20 |
- |
1mg |
Short Acting |
|||||
Midazolam1 (Versed®) |
Most Rapid IV |
0.5-1 (IV ) |
1-4 |
- |
- |
2 Rapid onset = within 15 minutes, Intermediate = 15-30 minutes, Slow = 30-60 minutes
References:
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.