Antibiotic therapy for Subdural Empyema

ü Subdural empyema (SDE) is a collection of pus between dura mater and arachnoid mater.

ü Empirical antibiotic therapy should consists of:

· ceftriaxone 2g IV infusion BD

· metronidazole 500mg IV infusion TDS

· vancomycin IV 1g BD

ü Adjust the antibacterials accordingly once organism identified and sensitivities known

ü Continue treatment until abscess resolved for a minimum of 6 weeks.

References:

1. A Review of Subdural Empyema and Its Management. http://journals.lww.com/infectdis/Fulltext/2007/05000/A_Review_of_Subdural_Empyema_and_Its_Management.6.aspx

2. NHS Antibiotic Guidelines. Treatment and Prophylaxis for Adults.