Tuberculoma

• Tuberculomas are conglomerate granulomatous foci within the brain parenchyma, and is one of the many forms of central nervous system tuberculosis (extra-pulmonary tuberculosis).

	UpToDate	CPG 2012
Regimen	“intensive phase”: isoniazid, rifampin, pyrazinamide, and either fluoroquinolone or IV aminoglycoside, administered daily for 2 months. “continuation phase”: isoniazid and rifampin admininistered daily or three times a week.	With standard anti-TB regimen as shown in table below. However, ethambutol penetrates poorly into even inflamed meninges, thus should be replaced with fluoroquinolones
Duration	18 months	Minimum of 6 months

References: 

1. UpToDate. Central nervous system tuberculosis. http://www.uptodate.com/contents/central-nervous-system-tuberculosis?source=search_result&search=tuberculoma&selectedTitle=1~15#H18

2. CPG. Management of Tuberculosis. 3rd edition. Nov 2012.