Thursday, May 14, 2015

Hormonal Therapies in Hospital Keningau


Medications
Date started
0
14
21
28
Progynova [28’s] (Estradiol Valerate)
    ·      HRT for symptoms secondary to oestrogen deficiency due to natural menopause or castration.
    ·      Prevention of menopausal osteoporosis.
Estradiol Valerate
Femoston [28’s] (Estradiol 1mg and dydrogesterone 10 mg)
    ·      HRT in naturally/ surgically induced menopause with intact uterus.
Estradiol 1 mg
Estradiol 1mg, dydrogesterone 10 mg
Menorest [28’s] (Tibolone 2.5 mg)
    ·      Menopause symptoms contraindicated / intolerant to other treatments.
Tibolone 2.5 mg
Loette [21’s] (Levonorgestrel 100 mcg, Ethinylestradiol 20 mcg)
    ·      Contraception
    ·      Moderate acne non-responsive to conventional therapy in premenarchal, premenopausal women 14 years old.
    ·      Non-contraceptive benefits:
Levonorgestrel 100 mcg, Ethinylestradiol 20 mcg

-
Progyluton [21’s] (Estradiol 2 mg and Norgestrel 0.5 mg)
    ·      Treatment of oestrogen deficiency secondary to menopause, hypogonadism, castration or primary ovarian failure in women with intact uterus.
    ·      Prevention of postmenopausal osteoporosis.
    ·      Control of irregular menstrual cycle.
    ·      Treatment of primary and secondary amenorrhea.

Estradiol 2 mg (10d)
Estradiol 2 mg,
Norgestrel 0.5 mg (11d)

-
Premarin [28’s] (Conjugated oestrogen 0.3 mg or 0.625 mg)
    ·      Oestrogen deficiency in females (0.3-1.25 mg OD)
    ·      Osteoporosis (0.3 mg OD).
    ·      Vasomotor symptoms, atrophic vaginitis and atrophic urethritis associated with hypoestrogenism. (Topical preferred) (0.3-1.25 mg OD).

Conjugated oestrogen


Ravimed (Medroxyprogesterone Acetate 5 mg)
Renal cell & endometrial carcinoma
200- 400 mg OD
Breast carcinoma
500 mg OD
Endometriosis
10 mg TDS X 90 days
Abnormal uterine bleeding/ secondary amenorrhea


2.5- 10 mg X 10/7
Continue for 3 consecutive cycles.


2.5- 10 mg X 5/7
Continue for 3 consecutive cycles.
Adjunct of cyclic oestrogen therapy

10- 20 mg OD for the last 7 days of each cycle.
Table1: Administration of Hormonal Therapies

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