Hormonal Therapies in Hospital Keningau

Medications	Date started
	0	14			21		28
Progynova [28’s] (Estradiol Valerate)
·      HRT for symptoms secondary to oestrogen deficiency due to natural menopause or castration.     ·      Prevention of menopausal osteoporosis.	Estradiol Valerate
Femoston [28’s] (Estradiol 1mg and dydrogesterone 10 mg)
·      HRT in naturally/ surgically induced menopause with intact uterus.	Estradiol 1 mg				Estradiol 1mg, dydrogesterone 10 mg
Menorest [28’s] (Tibolone 2.5 mg)
·      Menopause symptoms contraindicated / intolerant to other treatments.	Tibolone 2.5 mg
Loette [21’s] (Levonorgestrel 100 mcg, Ethinylestradiol 20 mcg)
·      Contraception     ·      Moderate acne non-responsive to conventional therapy in premenarchal, premenopausal women ≥ 14 years old.     ·      Non-contraceptive benefits:	Levonorgestrel 100 mcg, Ethinylestradiol 20 mcg						-
Progyluton [21’s] (Estradiol 2 mg and Norgestrel 0.5 mg)
·      Treatment of oestrogen deficiency secondary to menopause, hypogonadism, castration or primary ovarian failure in women with intact uterus.     ·      Prevention of postmenopausal osteoporosis.     ·      Control of irregular menstrual cycle.     ·      Treatment of primary and secondary amenorrhea.	Estradiol 2 mg (10d)		Estradiol 2 mg, Norgestrel 0.5 mg (11d)				-
Premarin [28’s] (Conjugated oestrogen 0.3 mg or 0.625 mg)
·      Oestrogen deficiency in females (0.3-1.25 mg OD)     ·      Osteoporosis (0.3 mg OD).     ·      Vasomotor symptoms, atrophic vaginitis and atrophic urethritis associated with hypoestrogenism. (Topical preferred) (0.3-1.25 mg OD).	Conjugated oestrogen
Ravimed (Medroxyprogesterone Acetate 5 mg)
Renal cell & endometrial carcinoma	200- 400 mg OD
Breast carcinoma	500 mg OD
Endometriosis	10 mg TDS X 90 days
Abnormal uterine bleeding/ secondary amenorrhea				2.5- 10 mg X 10/7 Continue for 3 consecutive cycles.
						2.5- 10 mg X 5/7 Continue for 3 consecutive cycles.
Adjunct of cyclic oestrogen therapy						10- 20 mg OD for the last 7 days of each cycle.

Table1: Administration of Hormonal Therapies