Treatment of acute
Wernicke-Korsakoff syndrome
- Two pairs of Pabrinex 5mL ampoules should be administered three times daily for two days.
- If there is no clinical response after two days (six doses), treatment should be discontinued.
- If clinical improvement is seen the contents of one pair of 5mL Pabrinex ampoules should then be administered three times daily for a further three days or for as long as clinical improvement continues.
High risk of
Wernicke-Korsakoff syndrome.
- One pair of Pabrinex 5mL ampoules administered three times daily for two days.
- Following the initial intravenous loading dose, oral supplementation should begin with thiamine 100mg three times daily.
- This should be reviewed prior to discharge.
Rapid therapy of
severe depletion or malabsorption of water soluble vitamins B and C,
particularly in alcoholism
- 2 to 3 pairs of 5ml ampoules (1 pair = ampoule 1 + ampoule 2) diluted with 50ml to 100ml of infusion solution and injected over 30 minutes at intervals decided by your doctor (typically every 8 hours).
Psychosis following
unconsciousness from a narcotic drug (narcosis) or electroconvulsive therapy,
or poisoning from infection
- 10ml of the mixed vials (1 pair) injected twice daily for up to 7 days.
Haemodialysis
patients
- 10ml of the mixed vials (1 pair) injected at the end of dialysis, once every 2 weeks.
Refeeding syndrome
- Pabrinex one to two pairs once to three times daily for 3 to 5 days (use the higher more frequent dose for chronic alcohol abusers.
REFERENCE
NHS Grampian
(http://www.nhsgrampian.com/grampianfoi/files/VitSupAC_503_1111.pdf)
Intensive Care
Society Of Ireland
(http://www.criticalcarenutrition.com/docs/BOB/ENPNGuideline.pdf)
Beaumont Hospital's
Intensive Care Unit's
(http://www.criticalcarenutrition.com/docs/BOB/BeaumontGuidelines.pdf
Product Leaflet
BNF
Hi can i ask why is parentrovite exist as 1 pair? Am really curious about it. Thx for your reply:)
ReplyDeletehi. both vials contain water soluble vitamins. the most likely reason for the separation would be to extend the stability of the component. we are awaiting feedback from the manufacturers on this. will update you once we get a reply.
Delete