Calcium Gluconate dosing for hypocalcemia in Pediatrics

Calcium Gluconate 10% / 10ml

1ml = 8.9 mg of calcium

1g of Calcium gluconate salt = 93mg of elemental calcium

1ml = 0.22 mmol

1) Dosing:

• For hypocalcemia (dose depends on clinical condition and serum calcium level)

Intravenous: 

Frankshaan	0.5 ml/kg  (10% calcium gluconate) (Max: 20 ml)                                       or 4.45 mg/kg (in elemental calcium) (Max: 178 mg)
Drugs.com	4.65 mg/kg to 11.6 mg/kg (dosing in elemental calcium)
BNF for Children	For Fast correction 0.5 ml/kg  (10% calcium gluconate) (Max: 20 ml) via slow infusion over 5-10 mins For Maintenance 4.5 ml/kg over 24 hrs

2) Administration:

• Oral

Administer with plenty of fluids with or following meals. The 10% calcium gluconate injection may be administered orally in young pediatrics.

• IV

It is usually administered slowly; not exceeding 200mg/min except in emergency situations through a small needle into a large vein in order to avoid too rapid increase in the serum calcium and extravasation. It is recommended that Calcium Gluconate injection be diluted with either 0.9%NaCl, 5% Glucose in Water, Lactate Ringers Injection or 5% glucose in 0.9%NaCl when intended to be administered as an IV infusion.

References:

1. http://www.drugs.com/dosage/calcium-gluconate.html
2. Frankshaan 16th Edition 2014
3. Lexicomp
4. BNF For Children 2014