Tuesday, July 14, 2015

Maximum dose of Neurobion

Content:
Thiamine 100mg , Pyridoxine 200mg, Cyanocobalamin 200mcg
Recommended dose:

  • 1 tablet 3 times daily
  • No information on maximum dose
  • Maximum dosing based on individual components

Thiamine 

  • usual dose of thiamine is 5-30 mg daily in either a single dose or divided doses for one month.
  • The typical dose for severe deficiency can be up to 300 mg per day

Pyridoxine 

  • 20-50mg TDS (B6 deficiency)
  • 100-400 g daily in divided doses (sideroblastic anaemia)
  • Long term use in doses above 200mg has been associated with neuropathy

Cyanocobalamin

  • Bioavailability is approximately 25%
  • Adults: 50-6000 mcg/ day

References:
MOH Drug Formulary
https://ods.od.nih.gov/factsheets/Thiamin-HealthProfessional/
http://www.drugs.com/dosage/thiamine.html
http://www.drugs.com/dosage/pyridoxine.html
http://www.drugs.com/ppa/cyanocobalamin-vitamin-b12.html

No comments:

Post a Comment

Note: Only a member of this blog may post a comment.