Wednesday, July 8, 2015

Zuclopenthixol Drops

1 drop = 1mg Zuclopenthixol
1ml = 20mg Zuclopenthixol

  • Bioavailability is about 44%
  • The maximum serum concentration is achieved at about 4 hours
  • Half life is about 20 hours

Dosing

  • Only for psychoses with insight or compliance
  • Acute Schizophrenia and Other Acute Psychoses; Severe Acute States of Agitation; Mania: Oral treatment: Usually 10-50 mg/day. 
  • In moderate to severe cases initially 20 mg/day increased, if necessary, by 10-20 mg/day every 2-3 days to ≥75 mg daily
  • Oral maximum dose is 100mg/day for acute psychosis

Administration:

  • Can be mixed with flavoured drinks, e.g. apple or orange juice
  • Can be taken with or without food
  • Storage:
  • Stored at max 15 C

Reference:

  • Product Information Leaflet
  • http://online1.mimsgateway.com.my/
  • lexicomp

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