Tuesday, August 25, 2015

Topical treatment for Genital Warts

Drugs
Administration
Podophyllotoxin

Topical As 15% (Indian podophyllum) or up to 25% soln (American podophyllum): Apply weekly, leave for 1-6 hr then wash off. If there is no improvement after 6 wk, stop treatment.
Imiquimod 5 % w/w Cream
(available in Blue Book)
 As 5% cream: Apply 3 times wkly for up to 16 wk. Cream is applied at night and left on the skin for 6-10 hr. Wash with mild soap and water after each dose. 
Sinecatechin ointment
Applied three times daily (0.5-cm strand of ointment to each wart) using a finger to ensure coverage with a thin layer of ointment until complete clearance of warts.
Pedophyllin resin 10%–25%
Applied to each wart and allowed to air-dry before the treated area comes into contact with clothing; over application or failure to air dry can result in local irritation caused by spread of the compound to adjacent areas. The treatment can be repeated weekly, if necessary.
Trichloroacetic acid (TCA) or Bichloroacetic acid (BCA) 80%–90%
A small amount should be applied only to the warts and allowed to dry before the patient sits or stands, at which time a white frosting develops.

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