Monday, October 26, 2015

WHO SHOULD NOT RECEIVE EXPRESSED BREAST MILK (EBM)

Human milk contains antibodies and other protective factors, but in the case of certain pathogens, it may also pose a possible risk of infection for the infant. The benefits for the infant to continue receiving EBM must be considered against the possible severity of the disease. It would be wise if the breast milk that is to be given to infants are tested for pathogens and the risks that the milk could expose are being elucidated first, before consumption. Here are some measures that could done to reduce the risk of infants receiving milk that is dangerous to them:



Risk Assessment of the Source (non-birth) Mother:

An assessment of the clinical status of the source mother at the time of breast milk collection/expression or feeding with regard to:

  • the presence of fever
  • the presence of rash (including vesicles on the breast), and
  • the presence of mastitis, breast abscess or bleeding nipple.
Checking the source mother’s antenatal serology for previous results, e.g. syphilis, hepatitis C (HCV) antibodies, hepatitis B (HBV), and Human Immunodeficiency virus (HIV) antibodies.

Checking for a history of HBV vaccination.

Checking medications prescribed to the source mother.

Where recent serological results are lacking, discussing risk factors for blood borne viruses (HIV, HBV and HCV) and syphilis in the source mother. These include:

  • Injecting drug use
  • Birthplace or previous residence or travel in a country with high prevalence of HIV or other blood borne viruses (as identified by an appropriate specialist)
  • Tattoo or piercing
  • History of syphilis (including date and treatment)
  • Blood transfusion history or possible iatrogenic exposure to a blood borne virus, and
  • Unprotected sex with a partner who has or is at risk of having a blood borne virus

Serological & Breast Milk Screening:

Testing should be expedited, in order to inform appropriate treatment to the baby, should it be required. It is recommended that at the time of the exposure the following should be collected from the source mother and the mother of the exposed baby:



Blood

HIV RNA NAT, HIV proviral DNA (if available) and HIV antibody/ antigen test.

However this information will be unlikely to be available in time to guide initiation of prophylactic therapy of the baby.


HCV antibody test, HCV RNA test


HBV surface antigen, HBV core antibody


Breast Milk

Cytomegalovirus (CMV) NAT (if baby is less than one month of age, or has underlying immune deficiency illness)



References:
1. Maternity-breast milk: Safe management <http://www.health.nsw.gov.au/policies/>
3. Malaysian Dietary Guideline

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