Medications In Anaphylaxis

DRUGS/INDICATION	CHILDREN	ADULTS
acute onset epinephrine (IM)	0.01 mg/kg (as a 1:1000 solution) IM every 5-15 minutes, maximum 0.3 mg/dose;	0.3 to 0.5 mg (as a 1:1000 solution) IM every 5-15 minutes
cardiopulmonary arrest epinephrine (IV) severe hypotension epinephrine (IV)	children: 0.01 mg/kg (as a 1:10,000 solution) intravenously every 3-5 minutes, maximum 1 mg/dose;	1 mg (as a 1:10,000 solution) intravenously every 3-5 minutes
	children: 0.01 mg/kg (as a 1:10,000 solution) intravenously every 5 minutes, maximum 0.3 mg/dose;	0.1 mg (as a 1:10,000 solution) intravenously every 5 minutes
Adjunct severe hypotension glucagon	children: consult specialist for guidance on dose;	5 mg intravenously initially, may repeat in 10-15 min if no response, followed by 5-15 micrograms/min if response seen
persistent respiratory symptoms salbutamol inhaled:	children: 0.15 mg/kg nebulized every 20 minutes for 3 doses, then 0.15 to 0.3 mg/kg every 1-4 hours when required;	1.25 to 5 mg nebulized every 20 minutes for 3 doses, then every 1-4 hours when required
symptomatic hives and rhinorrhoea diphenhydramine + ranitidine:	children: 1-2 mg/kg intravenously/intramuscularly; children: 1 mg/kg intravenously given over 5 minutes;	25-50 mg intravenously/intramuscularly 50 mg intravenously given over 5 minutes
post-emergency stabilisation methylprednisolone: prednisolone:	children and adults: 1-2 mg/kg/day intravenously children and adults: 0.5 to 1 mg/kg/day orally

 references:

Best Practice/BMJ