Syrup Amoxycillin to Erythromycin Conversion

	Amoxycillin	Erythromycin
Availability	125mg/5ml	EES 200mg/5ml
Dose	- 20 mg/kg/day 8 hrly. Severe infections  - 40 mg/kg/day 8 hrly	Mild-to-moderate infections: - 30-50 mg/kg/day PO divided q6-12hr Severe infection: - 60-100 mg/kg/day PO divided q6-12hr The recommended dosing schedule of erythromycin may result in gastrointestinal upset. Patients may require an alternative macrolide or a change to 3-times-daily dosing
Organisms	- provides good coverage of most infectious agents - not effective against Mycoplasma and Legionella species	- staphylococcal and streptococcal infections - most potential etiologic agents in rhinosinusitis, including Mycoplasma species - less active against H influenzae added advantage of being a good anti-inflammatory agent by inhibiting migration of polymorphonuclear leukocytes.

Reference:

http://emedicine.medscape.com/article/302460-medication#3