Oral Hyoscine Dosing in Paediatric

Availability

• Tablet Hyoscine 10mg
• Syrup Hyoscine 1mg/ml

Dosing recommendations

Reference	Age	Dosing
Frank Shann	None	·         0.5mg/kg TDS-QID
BNF for Children	6-12 years	Symptomatic relief of GI disorder ·         10 mg TDS
	4-10 years	Motion sickness ·         0.075-0.15mg 30 min before journey, repeated every 6h (max 3 doses/day)
	1m -2 years 2-5 years	Bowel Colic in palliative care ·         0.3-0.5/mg TDS-QID ·         5 mg TDS-QID
Drug Leaflet	6-12 years	GI and Colonic Spasm ·         10 mg TDS

Concerns

Cautious	·         Children (especially Down Syndrome) ·         Not used in children with Gastro-oesophageal reflux disease, diarrhoea, ulcerative colitis
Contraindicated	·         Myasthenia gravis ·         Paralytic ileus ·         Pyloric stenosis ·         Toxic megacolon