Wednesday, February 24, 2016

Oral Hyoscine Dosing in Paediatric


Availability
  • Tablet Hyoscine 10mg
  • Syrup Hyoscine 1mg/ml
Dosing recommendations
Reference
Age
Dosing
Frank Shann
None
·         0.5mg/kg TDS-QID
BNF for Children

6-12 years
Symptomatic relief of GI disorder
·         10 mg TDS

4-10 years
Motion sickness
·         0.075-0.15mg 30 min before journey, repeated every 6h (max 3 doses/day)

1m -2 years
2-5 years
Bowel Colic in palliative care
·         0.3-0.5/mg TDS-QID
·         5 mg TDS-QID
Drug Leaflet

6-12 years
GI and Colonic Spasm
·         10 mg TDS

Concerns

Cautious
·         Children (especially Down Syndrome)
·         Not used in children with Gastro-oesophageal reflux disease, diarrhoea, ulcerative colitis
Contraindicated
·         Myasthenia gravis
·         Paralytic ileus
·         Pyloric stenosis
·         Toxic megacolon

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