Conversion of Carvedilol to Bisoprolol

• Switch from carvedilol to bisoprolol in a 5:1 conversion
• Summary of conversion 

Carvedilol	Bisoprolol
3.125mg twice daily	1.25mg once daily
6.25mg twice daily	2.5mg once daily
12.5mg twice daily	5mg once daily
25mg twice daily (may titrate to 50mg twice daily if > 85 kg)	10mg once daily

References : 

1. PBM-MAP Recommendations for Use of Beta-Adrenergic Blockers in HF: www.pbm.va.gov/clinicalguidance/clinicalrecommendations/BetaAdrenergicBlockersHeartFailureClinicalRecommendations.doc+&cd=1&hl=en&ct=clnk
2. Therapeutic Interchange of Carvedilol to Bisoprolol for Chronic Heart Failure: The Singapore Experience: Retrieved from http://www.ajpb.com/journals/ajpb/2012/ajpb_mayjun2012/therapeutic-interchange-of-carvedilol-to-bisoprolol-for-chronic-heart-failure-the-singapore-experience#sthash.Ti7joXh9.dpuf
3. 2013 ACCF/AHA Guideline for the Management of Heart Failure: Retrieved from http://circ.ahajournals.org/content/128/16/e240.extract .
4. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: Retrieved from http://circ.ahajournals.org/content/112/12/e154.full.pdf+htm
5. Switching and Uptitrating Beta Blockers in Heart Failure : http://www.swmit.nhs.uk/pdf+/CIOS/cios2010709.pdf