Adminstration of Nivestim (Filgrastim)

•  Availability: 30MU (300mcg) / 0.5 ml

Storage

• Store and transport refrigerated (2°C – 8°C). Do not freeze.
• Keep the pre-filled syringe in the outer carton in order to protect from light.
• The syringe can be removed from the refrigerator and left at room temperature for a single period of maximum 7 days (but not above 25°C).
• Do not use Nivestim if you notice it is cloudy or there are particles in it

Administration

• Remove the Nivestim syringe from the fridge and allow it to reach room temperature (approximately 25 °C). This will take 15–30 minutes.
• Hold the syringe with the needle pointing upwards.
• Remove the protective cap from the injection needle. The syringe is now ready for use.
• You may notice a small air bubble in the syringe. You do not have to remove the air bubble before injecting. Injecting the solution with an air bubble present is harmless
• Clean the area of skin with an antiseptic wipe
• 
• Pinch a large area of skin, taking care not to touch the area you have cleaned.
• With your other hand, insert the needle at an approximate 45˚ angle
• Pull the plunger back slightly to check if any blood appears in the syringe. If you do see blood inside the syringe, remove the needle and re-insert it in a different site.
• Depress the plunger while grasping the finger flange until the entire dose has been given. The passive needle guard will NOT activate unless the ENTIRE dose has been given

• Remove the needle from your skin, then let go of the plunger and allow the syringe to move up until the entire needle is guarded and locks into place
• Ensure the needle guard covers the needle

•  videa at http://www.medicininstruktioner.se/pfizer/nivestim/

Reference:

• Nivestim Package Information Leaflet