Mannitol

Availability:

• Mannitol 10% (INFUSOL®M10)
• Mannitol 20% (INFUSOL®M20)

Composition:

                                             10%                                     20%

Mannitol                                10g                                       20g

Water for Injection to          100mL                                  100mL

Osmolarity                        550mOsm/L                       1100mOsm/L

Dosing and Administration for Diuretic:

Adult	Paediatric
Dose: 50-100 gram of Mannitol   Administration: rate adjusted to maintain urine flow of at least 30-50mL per hour.	Dose: 0.25-2g/kg  Administration: 2-6 hours

Dosing and Administration for Cerebral Oedema or Elevated Intracranial Bleeding or Glaucoma:

Adult	Paediatric
Dose: 0.25-2g/kg Administration: 30 to 60 minutes	Dose: 1-2g/kg  Administration: 30 to 60 minutes

 

References:

1. INFUSOL®M10 and M20 product Information

2. http://www.rxlist.com/mannitol-iv-drug.htm

3. Micromedex

4. Lexicomp

5. Formulari Ubat KKM, March 2016.