Friday, September 29, 2017

Mannitol

Availability:
  • Mannitol 10% (INFUSOL®M10)
  • Mannitol 20% (INFUSOL®M20)
Composition:
                                             10%                                     20%
Mannitol                                10g                                       20g
Water for Injection to          100mL                                  100mL
Osmolarity                        550mOsm/L                       1100mOsm/L

Dosing and Administration for Diuretic:


Adult
Paediatric
Dose: 50-100 gram of Mannitol  

Administration: rate adjusted to maintain urine flow of at least 30-50mL per hour.

Dose: 0.25-2g/kg

 Administration: 2-6 hours

Dosing and Administration for Cerebral Oedema or Elevated Intracranial Bleeding or Glaucoma:

Adult
Paediatric
Dose: 0.25-2g/kg

Administration: 30 to 60 minutes

Dose: 1-2g/kg

 Administration: 30 to 60 minutes
 

References:
1. INFUSOL®M10 and M20 product Information
3. Micromedex
4. Lexicomp
5. Formulari Ubat KKM, March 2016.

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