Safety of Essential Phospholipid (Livovid - MAL06061350X) in Breastfeeding

Product Leaflet : Not mentioned

Active Ingredient	Recommendation during Breastfeeding
Lecithin	·         Supplemental lecithin has been recommended as a treatment for plugged milk ducts and as an additive to human milk that is given to preterm infants via pumping through plastic tubing in order to prevent fat loss. ·         No scientifically valid clinical studies exist on the safety and efficacy of high-dose lecithin supplementation in nursing mothers or infants.
Thiamine	·         There are no data on the excretion of thiamine into human milk. ·         The manufacturer recommends that caution be used when administering thiamine to nursing women. ·         The recommended daily allowance (RDA) for thiamine during lactation is 1.4 mg/day regardless of a woman's age. Women who are breast-feeding more than one infant may have increased needs for thiamine.
Riboflavine	·         Safe to take during pregnancy and while breastfeeding, when taken in the dose recommended for your age and condition. ·         Any higher-than-recommended dose could have unknown effects on a pregnant woman's unborn baby. ·         Pregnant women shouldn't take more than 1.4 mg of riboflavin a day, and the recommended daily intake for breastfeeding women is 1.6 mg.
Pyridoxine	Caution is recommended. Excreted into human milk: Yes Comments: -Pyridoxine needs are increased during lactation. -Concentrations in breast milk are directly proportional to dietary intake. -Very large pyridoxine doses are reported to inhibit lactation; doses closer to physiologic levels had no effect on lactation.
Cyanocobalamin	Use is not recommended; benefit to mother should outweigh risk to the infant. (AU) Excreted into human milk: Yes
Nicotinamide	·         Niacin is actively excreted into breast milk. ·         It is unknown if niacinamide is excreted into breast milk, but it is probable that it also is actively transferred. ·         The National Academy of Sciences recommended dietary allowance for niacin is 20 mg. If the diet of the lactating woman adequately supplies this amount, supplementation with niacinamide is not needed. ·         Maternal supplementation with the RDA for niacinamide is recommended only for those patients with inadequate nutritional intake. ·         Niacinamide use in excess of the recommended daily allowance (RDA) during lactation should be avoided.
Vitamin E	Use is considered acceptable. Excreted into human milk: Yes

Content per capsule:

Active Ingredient	Strength
Lecithin	500mg
Thiamine	3mg
Riboflavine	3mg
Pyridoxine	3mg
Cyanocobalamin	3mcg
Nicotinamide	15mg
Vitamin E	3.3mg

References:

1. Product  Leaflet
2. Lecithin https://www.ncbi.nlm.nih.gov/books/NBK501772/
3. Thiamine Pregnancy and Breastfeeding Warnings Assessed from https://www.drugs.com/pregnancy/thiamine.html
4. What Is Riboflavin (Vitamin B2)? https://www.everydayhealth.com/drugs/riboflavin
5. Pyridoxine Pregnancy and Breastfeeding Warnings https://www.drugs.com/pregnancy/pyridoxine.html
6. Cyanocobalamin Pregnancy and Breastfeeding Warnings https://www.drugs.com/pregnancy/cyanocobalamin.html
7. Niacinamide Pregnancy and Breastfeeding Warnings https://www.drugs.com/pregnancy/niacinamide.html
8. Vitamin e Pregnancy and Breastfeeding Warnings  https://www.drugs.com/pregnancy/vitamin-e.html

Prepared by Nur Nabiha R. on 10.03.2020