Pharmacological Treatment For Venous Ulcer

Available products in HKGU

Generic  name	Brand name
Acetylsalicylic acid 300mg	Uniaspirin

Treatment for venous ulcer

Generic name	Brand name	Dose & Frequency	Notes
Pentoxifylline 400mg	Trental	400mg TDS	Up to 6 months
Acetylsalicylic acid 300mg	Aspirin	300mg  OD	-

*Other treatment options (there is insufficient evidence to recommend its use):

• Micronized purified flavonoid fraction

• Mesoglycan

• Zinc (oral)

• Iloprost

REASONING

Pentoxifylline

• Inhibitor of platelet aggregation

• Reduces blood viscosity and, in turn, improves microcirculation

Aspirin

• Increase ulcer healing time and reduce ulcer size

• There is insufficient evidence on which to base a recommendation for aspirinin chronic venous leg ulcer

REFERENCE:

American Family Physician (http://www.aafp.org/afp/2010/0415/p989.html)

SIGN Guidelines (http://www.sign.ac.uk/pdf/sign120.pdf)