Thursday, July 28, 2016

Alfacalcidol : Via Ryles Tube

Availability:
  • Soft gel capsule or 250mcg and 500mcg
Administration
  • Manufacturer do not recommend opening the capsules owing to the risk of administering an incomplete dose
Administration Capsule
  • With capsules, the gelatin is usually a binding agent in the capsule rather than in the medicine itself.
  • A simple alternative can be to to pierce liquid-containing capsules and squeeze the liquid onto a spoon
  • No information available on stability of solution with food or milk, thus advice for direction administration into mouth of infants
Recommendations:
  • Use of oral drops (2mcg/drop)
  • A prolonged break in the feed in not required
  • Several references also uses One-Alpha injection orally or via feeding tube
References:
  1. https://www.medicines.org.uk/emc/medicine/1030
  2. stockportccg.org/wp-content/uploads/2012/01/34838_Med_Admin_Dysphagia.pdf
  3. NEEMMC GUIDELINES FOR TABLET CRUSHING AND ADMINISTRATION VIA ENTERAL FEEDING TUBES
  4. Handbook of Drug Administration via Enteral Feeding Tubes

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