Alfacalcidol : Via Ryles Tube

Availability:

• Soft gel capsule or 250mcg and 500mcg

Administration

• Manufacturer do not recommend opening the capsules owing to the risk of administering an incomplete dose

Administration Capsule

• With capsules, the gelatin is usually a binding agent in the capsule rather than in the medicine itself.
• A simple alternative can be to to pierce liquid-containing capsules and squeeze the liquid onto a spoon
• No information available on stability of solution with food or milk, thus advice for direction administration into mouth of infants

Recommendations:

• Use of oral drops (2mcg/drop)
• A prolonged break in the feed in not required
• Several references also uses One-Alpha injection orally or via feeding tube

References:

1. https://www.medicines.org.uk/emc/medicine/1030
2. stockportccg.org/wp-content/uploads/2012/01/34838_Med_Admin_Dysphagia.pdf
3. NEEMMC GUIDELINES FOR TABLET CRUSHING AND ADMINISTRATION VIA ENTERAL FEEDING TUBES
4. Handbook of Drug Administration via Enteral Feeding Tubes