Thursday, July 28, 2016

Cordyceps: Interactions


  • Cordyceps is a fungus that lives on certain caterpillars in the high mountain regions of China
Rationale For Use
Safety
  • Cordyceps is POSSIBLY SAFE for most people when taken appropriately by mouth, short-term
Pregnancy and breast-feeding:
  • There is not enough reliable information about the safety of taking cordyceps if 
  • Stay on the safe side and avoid use
Interactions
Cyclophosphamide
  • might decrease the effectiveness of cyclophosphamide
Immunosuppressants
  • Cordyceps might increase the immune system.
  • Decrease the effectiveness of medications that decrease the immune system.
    Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.
Prednisolone
  • Prednisolone is sometimes used to decrease the immune system.
  • Taking cordyceps might make prednisolone less effective for decreasing the immune system.
Drugs that increase the risk of bleeding
  • aspirin, anticoagulants (blood thinners) such as warfarin (Coumadin®) or heparin, antiplatelet drugs such as clopidogrel (Plavix®), and nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).
  • Multiple cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto
Antidiabetic Medications
  • Cordyceps may lower blood sugar levels.
  • Caution is advised in people with diabetes or hypoglycemia, and in those taking drugs, herbs, or supplements that affect blood sugar.
  • Blood glucose levels may need to be monitored
Antihypertensives
  • Cordyceps may cause low blood pressure.
  • Caution is advised in people taking drugs or herbs and supplements that lower blood pressure.
Bleeding disorders
  • Cordyceps might slow blood clotting.
  • might increase the risk of bleeding in people with bleeding disorders.
Surgery
  • might increase the risk of bleeding during surgery.
  • Stop taking cordyceps 2 weeks before surgery
References:
  1. http://www.webmd.com/vitamins-supplements/ingredientmono-602-cordyceps.aspx?activeingredientid=602
  2. http://www.wellness.com/reference/herb/cordyceps-cordyceps-sinensis/dosing-and-safety
  3. https://www.drugs.com/npp/cordyceps.html
  4. http://www.rxlist.com/cordyceps-page3/supplements.htm#Interactions

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