- Vancomycin exhibits time dependent killing, which implies that maintaining trough serum concentrations above the MIC is the most important determinant of therapeutic outcome.
- Vancomycin given as a continuous infusion avoids high peak concentrations and allows the maintenance of a steady state concentration above the MIC
- Additional benefits of a vancomycin continuous infusion include:
- Less nursing time required for administration
- Random vancomycin levels can be obtained for therapeutic drug monitoring
- Less cost of acquisition and wastage
Dosing
Dilution and Preparation
Therapeutic Range
References:- Vancomycin Dosing - CHW. 23 February 2016
- https://www.ncbi.nlm.nih.gov/pubmed/23172265
- Vancomycin Dosing for Pediatrics University Health System
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.