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Monday, April 6, 2020

Beta Lactam Side Chains Comparison Table

Note:
Any space with alphabets, either capital R or small r, indicate that the two overlapping drugs have some similar side chain.

Therefore, choosing another drug that has no common side chain may help to eliminate the cross-allergy risk - HOWEVER, this is only true if the patient is NOT:
(a) allergic to the whole group of penicillin / cephalosporin / carbapenem OR
(b) allergic to all beta lactam members.

Statistically, based on literature, there is 5-25% chance of cross allergy between peniciilin and cephalosporin.

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