Treatment Options For Keloids

Types of keloids

Scar type	Characteristics	Maturation
Minor keloid	Focally raised Pruritic Extends beyond burn borders May have genetic component for keloid development Typical site: earlobes	May develop one year after burn Does not regress spontaneously Recurrence generally follows surgical excision
Major keloid	Large (>0.5 cm) Painful Pruritic Extends beyond burn borders over normal tissue Can result even from minor trauma	Does not spontaneously regress  Can continue to progress in size over the years

Available Product In HKGU

Generic name	Brand name
Triamcinolone Acetonide 40mg/ml Inj	Kenacort-A

Minor keloids (<0.5 cm)

• Triamcinolone acetonide 10 to 40 mg/mL 
• Repeated at four-week intervals
• Intralesional corticosteroid injections are painful. For local anesthesia, EMLA cream may be applied under occlusion for 1.5 hours before injection
• Second-line therapies, intralesional 5-FU in combination with intralesional corticosteroids (0.9 mL of 5-fluorouracil 50 mg/mL plus 0.1 mL of Triamcinolone acetonide 40 mg/mL)

Major keloids (>0.5cm)

• Intralesional Triamcinolone acetonide 40 mg/mL 
• Repeated at intervals of three to four weeks for four to six months

REFERENCE :

http://www.aafp.org/afp/2009/0801/p253.html

Indian Journal Of Dermatology, Venereology & Leprology

Uptodate