Dosing Strategy
Patient
|
Dose
|
Frequency
|
Ref
|
Insulin naïve patient
|
5 units
|
BD (Breakfast & Dinner)
|
Product brochure
|
Titration : every 3-4 days based on premeal BG to acheieve BG
<6.1mmol/L
|
|||
Converting from low mix twice daily
|
1/3 units from current dose
|
TDS
( Breakfast, Lunch & Dinner)
|
|
Converting from low mix three times daily
(Twice daily Humalog Mix 50 & Once Daily Humalog Mix 25)
|
1/3 Humalog Mix50 (Breatkfast & Lunch)
1/3 Humalog Mix25 (Dinner)
|
||
For any diabetic population
|
5 to 10 units once or twice daily
(prebreakfast
and/or presupper).
Titrate
: 1 unit everyday until blood glucose reached target level
|
Diabetec.ca
|
|
Type 1 /Type 2 patient
|
Type 1 : 0.3-1U/kg/day in divided doses
Type 2 : 0.5-1.5U/kg/day
|
Tarascon Pharmacopoeia 2014
|
Dose Adjustment
Average
glucose before meal (mmol/L)
|
Change
in insulin dose
|
Ref
|
<4.4
|
-2
|
Product brochure
|
4.4-6.1
|
0
|
|
6.1-7.7
|
+2
|
|
7.7-11.1
|
+4
|
References:
- Product Brochure
-
http://guidelines.diabetes.ca/Browse/Appendices/Appendix
- Eli Lilly Spokesperson
- http://guidelines.diabetes.ca/CDACPG_resources/Insulin_Prescription_May_5_2014.pdf
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