-
Drug
interactions with warfarin therapy are a common and significant
cause of morbidity and mortality and should be considered whenever
starting or stopping a drug (particularly antibiotics).
-
In
general, dose adjustments should only be made after checking the INR
at 48-72 hours after initiating an interacting medication.
-
The
INR should continue to be monitored every 48-72 hours for the course
of interacting medication therapy or until INR is again confirmed
stable.
-
Red: ++ The interaction may be life-threatening and/or require medical intervention to minimise or prevent serious adverse effects; or the drugs are contraindicated for concurrent use.
-
Black:
+ The interaction may result in an exacerbation of the patient’s
condition and/or require an alteration in therapy.
Reference
:
-
https://www.health.qld.gov.au/publications/clinical-practice/guidelines-procedures/medicines/warfarin-guidelines.pdf
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.