Test Dose for IM Iron Dextran

Test dose

• IM/IV Prior to the first IV or IM iron dextran injection, give a 0.5 mL test dose by the same route, respectively. 

General Advice

• IV test doses should be administered at a gradual rate over at least 30 sec or over at least 5 min.
• Anaphylactic reactions occurring following iron dextran injection are usually evident within a few min; however, at least 1 h should elapse before the remainder of the therapeutic dose is given.
• Discontinue oral iron preparations before administering parenteral iron products. Coadministration of parenteral iron preparations may reduce absorption of oral iron.
• For IM ( InFeD only) or IV administration only. Not for intradermal, subcutaneous, or intra-arterial administration.
• Do not administer if particulate matter or discoloration is noted.
• Do not mix with other IV medications or add to parenteral nutrition solutions for IV infusions.

IM injection

• Change needles between withdrawal of iron dextran from vial and injection to minimize staining of subcutaneous tissues.
• Inject prescribed dose deeply, using 2- or 3-inch, 19- or 20-gauge needle, into the muscle of the upper outer quadrant of the buttock (never into the arm or other exposed areas). To avoid injection or leakage into subcutaneous tissue, administer using Z-track technique (displacement of skin laterally prior to injection)
• If patient is standing, have patient bear weight on the leg opposite the injection site. If in bed, have patient in a lateral position with injection site uppermost.

References:

1.www.drugs.com