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Wednesday, June 3, 2015

Deworming Protocols In Children

Available products in HKGU

Generic Name
Brand Name

  • T. Albendazole 200mg
  • Syrup Albendazole 200mg/5ml


Zentel

Organisms
Dosage
Duration
Neurocysticercosis
<60kg:15mg/kg/day in 2 divided doses (max:800mg/day)
≥60kg:800mg/day in 2 divided doses
*Give concurrent anticonvulsant and corticosteroid
 (eg, dexamethasone or prednisolone) therapy during first week
8-30days
Hydatid
<60kg:15mg/kg/day in 2 divided doses (max:800mg/day)
≥60kg:800mg/day in 2 divided doses

Administer dose for three 28-day cycles with a 14-day drug free interval between each cycle
Cysticercus cellulosae (off label use)
15mg/kg/day  (max:800mg/day) in 2 divided doses
8-30 days, may be repeated as necessary
Echinococcus  granulosus (tapeworm)
15mg/kg/day  (max:800mg/day) divided twice daily
1-6 months
Giardia duodenalis  (giardiasis) (off label use)
10mg/kg/day
5 days
Microsporidiosis (other than Enterocytozoon bienuesi or V.corneae), disseminated or intestinal infection (HIV-positive, off label use)
15mg/kg/day (max:800mg/day) in 2 divided doses
Continued until immune reconstitution after HAART initiation
Ancylostoma caninum, Ascaris lumbricoides (roundworm), Ancylostoma duodenale (hookworm), and Necator americanus (hookworm) (off label use)
400mg
Single dose
Clonorchis sinensis (Chinese liver fluke) (off label use)
10mg/kg/day
7 days
Cutaneous larva migrans (off label use)
40mg once daily
3 days
Enterobius vermicularis (pinworm) (off label use)
400mg
Single dose, repeat in 2 weeks
Gnathostoma spinigerum (off label use)
800mg/day in 2 divided doses
21 days
Gongylonemiasis (off label use)
400mg once daily
3 days

Mansonella perstans (off label use)
800mg/day in 2 divided doses
10 days
Oesophagostomum bifurcum (off label use)
400mg
Single dose
Trichinella spiralis (Trichinellosis) (off label use)
800mg/day in 2 divided doses
8-14 days + corticosteroids for severe symptoms
Visceral larva migrans (toxocariasis) (off label use)
800mg/day in 2 divided doses
5 days

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