- This is the first line treatment for PCP
- Toxoplasmosis second line treatment regime is Bactrim (TMP 5 mg/kg and SMX 25mg/kg) IV or PO BD
OR
- Sulfadoxine/Pyrimethamine 500/25mg (Fansidar) PO 1 tab q12h + Folinic Acid 10-25mg PO q24h + Clindamycin 600mg IV/PO q6h for at least 6 weeks
- This is first line treatment for Toxoplasmosis
- Second line treatment for PCP involves Pyrimethamine (Leucovorin) + Clindamycin 600mg IV/PO q6h
- Pyrimethamine dose : 200mg PO once then followed by body weight: ≤ 60kg 50mg PO daily, > 60kg 75mg PO daily
References:
- Aidsinfo.nih.gov/guidelines
- National Antibiotic Guideline 2014
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