Side Effects:
- all antiplatelet drugs increase the risk of bleeding in the gastrointestinal tract and brain
- Clopidogrel (Plavix), prasugrel (Effient) and ticlopidine (Ticlid) have been linked to a condition known as thrombotic thrombocytopenic purpura (TTP)
- ticlopidine (Ticlid and generic) have a risk for TTP that’s much higher than those taking clopidogrel or prasugrel
- The danger of getting any of the three conditions—TTP, neutropenia, and aplastic anemia—is highest during the first three months of taking ticlopidine
- Clopidogrel and ticlopidine can also interact adversely with other medicines
References:
- Using Antiplatelet Drugs to Treat: Heart Disease, Heart Attacks, and Strokes Comparing Effectiveness, Safety, and Price
- Comparison of Oral Antiplatelets. PHARMACIST’S LETTER / PRESCRIBER’S LETTER
August 2014
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